CORE MANNA
Glyco Immune Aquaceutical Elixer
CORE MANNA
Glyco-Immune Support
We've Cracked The Genetic Code & We're Aiming For The Sweet Spot
Core Manna is the Product of a decade's worth of research, this revolutionary solution unlocks the body’s code to protect against pathogens, allergies, inflammation, and more!
Our proprietary groundbreaking glycobiology based formulation provides your body with the exact fuel it needs to support the entire system! With its unique blend of ingredients, Core Manna helps the body protect and rebuild itself during times of stress and infection with results that are limitless.
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We are exposed to millions of potential pathogens daily. Our body uses sugars, or glycans, to fight back. Our immune cells usually have no problem recognizing the sugars on our own cells as ‘self’, but when pathogens use decoys to look like healthy cells, it can be difficult for the body to know what’s real or not.
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Pathogens use ‘glycan shields’ and can alter sugar chains on the cell surface to avoid recognition. These foreigners have developed mechanisms to allow them to invade human cells, which forces the body to attack itself and shift its attention away from the pathogen. This may lead to undesired responses and symptoms in which one’s body attacks healthy cells rather than the pathogen.
Core Manna restores proper function with immune system signaling by glycoengineering, bioencoding, re-educating, and communicating all of the necessary components we need to establish 'self' vs. 'nonself' again for proper pattern recognition.
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It is the first supplement to bring together cutting-edge ingredients to bio sync the body's natural self-healing process. We believe in looking at the needs of the whole person and getting to the core of the matter - not just addressing symptoms, or symptoms of symptoms.
Core Manna Benefits
Core Manna supplies the system with a full spectrum of naturally occurring compounds providing your body with a multi-faceted approach to positively impact every system in the body. Core Manna’s proprietary blend is designed to address your nutritional needs and challenges by supplying vital nutrients that help regulate each body's system. This specialized formula makes it easier for you to live a healthy lifestyle, as well as enhance your mental, emotional, and physical performance.
Cellular Communication
If cells can't communicate they get divorced. Our cellular antenna, cilia, utilize glycoprotein-dependent adhesion mechanisms which enables cells to communicate and to interpret signals. Cellular communication is heavily relient on sugar chains.
Inflammation Resolution
Acute inflammation is the immune system's response to harmful pathogens, damaged cells, toxic compounds, and acts by removing injurious stimuli and initiating the healing process. Therefore, it is a defense mechanism that is vital to health. Chronic inflammation is deletarious and is characterized by marked changes in glycosylation.
Pathogen Protection
Host-pathogen interactions are fundamental to our understanding of infectious diseases. Pathogen protection is mediated through sugar chains presented on the cell surface. Glyconutrients play a vital role in preventing pathogen entry and act as a barrier of protection.
Enhanced Circulatory System Flow
The glycocalyx is a dense, gel-like meshwork made up uf sugar chains that surrounds the cell, constituting a physical barrier for any object to enter the cell. The endothelial glycocalyx plays an important role in vascular homeostasis with antithrombotic and anti-inflammatory functions.
Immune System Surveillance
Immune surveillance is a protective mechanism whereby the immune system recognizes and eliminates harmful pathogens. The majority of immune checkpoints are membrane glycoproteins. The cornerstone of a healthy immune system is the ability to distinguish “self” from “nonself” which is reliant on sugar chains.
Extracellular Matrix Mojo
The Extracellular Matrix (ECM) is a cohesive network of molecules linked to each other by glycoproteins that provide structural and biochemical support to surrounding cells. Glycosaminoglycans (GAGs) play a vital role within the Extracellular Matrix.
Nervous System Network Support
Glycosylation plays a critical role in the nervous system and regulates a number of Ion channels that control responses to environmental stimuli and voltage. Oligosaccharides are critical for brain and central nervous system function.
Circadian Clock Entrainment
External environmental cues, including light/dark cycles, food intake, stress, and exercise, provide important information for adjusting our interanl clock for the regulation of the sleep/wake cycles. Circadian clocks are regulated by protein glycosylation, glycogen metabolism, glucose transport and insulin sensitivity.
Heightened Brain Cognition
Glycolysis is essential for a variety of neural activities in the brain, including energy production, synaptic transmission, and redox homeostasis. In the brain, N-linked glycosylated proteins participate in a myriad of processes, from electrical gradients to neurotransmission.
Detoxification
Lysosomes are the garbage disposal units of our cells, roaming around digesting cellular waste with their specialized enzymes and recycling excess or worn-out cell parts. Lysosomes are also instrumental in the vital process of autophagy. Autophagy is the ultimate detox which removes and recycles unwanted or damaged molecules from your cells. Lysosomal proteins are heavily glycosylated.
Elevated Mitochondria Energy Production
The core interaction between mitochondrial metabolism, ATP production, and immune signaling has emerged as a central regulator of immune sensing. Mitochondrial functions, energy metabolism and protein glycosylation are interconnected processes.
RNA & DNA Synthesis
Nucleic acids, which are adenine, cytosine, guanine, thymine, and uracil, are essential to all known forms of life. They serve as the primary information-carrying molecules in cells and make up the genetic material. They create, encode, and then store information of every living cell of every life-form on Earth and transmit and express information to the next generation of each living organism.
How It Works
Health and nutrition are controlled by sugar molecules because the entire system is regulated by sugar chains. Glycoimmunology is the study of how specific types of sugar chains, or glycans, impact our immune system. The potential applications range from immune system development, autoimmunity, host-pathogen defense, and much, much more!
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The diversity of these complex sugar chains that form on the cell surface exceeds that even of DNA, with up to 25,000 genes, RNA, with approximately 360,000 mRNA, as every known cell is covered in glycans. Also, their structures exceed by orders of magnitude the number of the proteins encoded by our genome, which can be up to 400,000 proteins.
Simply put, they are essential to life. Without them, we would surely perish. In fact, the loss of any component of these bonded sugar molecules can result in dire consequences and incompatibility with life itself.
This makes supplying our bodies with the right types of Glyconutrients quintessentially SUPREME in all things health.
These synergetic compounds are found to be critical in supporting the function of the immune system, leading to healthy cellular metabolism, anti-inflammatory benefits, and so much more.
Core Manna's proprietary formulation has a unique blend of ingredients that contain nutrients your body uses to rebuild – after years of neglect, damage, stress, and improper nutrition.
We're excited to share with you more information about the Glycoimmunology principles that make up our immune system.
Using a simple acronym, we’re able to remember how these protections work together to keep us healthy.
"Be Sweet, and put a GAG Order on Pathogen Hijacking".
Complimenting The Sugar Code
Glycosaminoglycans (GAGs) are negatively-charged polysaccharide (sugar) compounds. They are essentially sulfated polysaccharides that are abundant in Sea Algae and Deer Velvet Antlers, for example.
GAGs play a key role in cell signaling, which serves to modulate a vast amount of biochemical processes. Some of these processes include the regulation of cell growth and proliferation, promotion of cell adhesion, anticoagulation, and wound repair, among many more.
The presentation of these GAGs can dictate whether positive or negative regulation of immune response occurs. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial pathogens, including viruses, bacteria, parasites, and fungi. Pathogens use GAGs at virtually every major portal of entry to promote their attachment and invasion of host cells, movement from one cell to another, and to protect themselves from immune attack. Pathogens co-opt fundamental activities of GAGs to accomplish these tasks.
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Glycosaminoglycans are used in the body as a lubricant for joints, for supporting connective tissues such as cartilage and tendons, and may even help assist with weight loss. Common GAGs include glucosamine, chondroitin sulfate, and hyaluronic acid.
Core Manna provides essential Glycosaminoglycans (GAGs) thereby restoring the balance and harmony of cells.
Enhanced Bioavailability
Core Manna utilizes the latest in cutting edge nanotechnology to increase maximum absorption and bioavailability. We've developed a proprietary Smart Carbon Oligosaccharide Nanoparticle Delivery System (SCONDS™) that incorporates five separate nanoparticle sizing technologies into one. An unprecedented monumental achievement!
At some point in time you may have encountered the belief that supplemental ingredients are too difficult for the body to absorb, and therefore of little use. And to be fair, there is some truth there; nutrients do have to be absorbed in order to be useful. To make natural compounds of any type more effective and consistent, they may require an extra boost.
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That’s where our proprietary Smart Carbon Oligosaccharide Nanoparticle Delivery System (SCONDS™) comes in. It allows the escort of ingredients through intestinal walls for better absorption, enhanced stability and bioavailability. In other words, a type of "programmed packaging".
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This advanced technology acts as a nanoparticle molecular container that surrounds other compounds until they are ready to be released directly into the cell. This process also naturally increases the shelf life of raw material. These nanocavities are stable core–shell nanoparticle encapsulated molecules which allow for the controlled release and direct cellular delivery of natural biomolecules over time, further increasing their beneficial effectiveness.
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Benefits may include:
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Nanoencapsulated aquaceutical delivery
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Amplified absorption
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Increased bioavailability
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Heightened bioactivity
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Enhanced molecular stability
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Advanced particle distribution
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Cutting-edge controlled release
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Extended shelf life
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These naturally occurring compounds encapsulate and preserve active compounds which allows them to act as nanoparticle molecular containers that surround other compounds until they are ready to be released. This process also naturally increases the shelf life of raw material.
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These glyconanocavities are stable core–shell nanoparticle encapsulated molecules which allow for the controlled release and direct cellular delivery of natural biomolecules over time, further increasing their beneficial effectiveness.
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Core Manna offers a unique advanced aquaceutical elixir that is designed to provide a wide range of health benefits for those looking to naturally improve their well-being. Our product combines natural herbal ingredients, with advanced nanotechnology to create a powerful, yet gentle elixir that can be used to enhance physical and mental health. We believe in the power of natural healing and are committed to providing the highest quality of care to our customers.
Quantum Harmonic Terahertz Wave
Resonance Technology
Quantum Harmonic Terahertz Wave Resonance Technology specifically works by interacting with water molecules. Glycerin is miscible with water and is hygroscopic (water attracting) by nature.
Quantum Harmonic Terahertz Wave Resonance Technology helps to build and maintain the natural structure of the water turning the water molecule into “informed water” with “quantum coherence” with a “buckyball-like” pentagonal dodecahedral structure. Or, water structured in the Golden Ratio.
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Pentagonal water clusters have been experimentally identified as being key to the hydration and stabilization of biomolecules. Such examples indicate the tendency of water pentagons to form closed geometrical structures at biomolecular interfaces including DNA, RNA, Proteins, and Amino acids. The “restructuring” or clustering of water molecules may even determine biological cell architecture and function.
Water—“restructured” as nanoclusters of the above-described type—plays a key role in the proper folding of proteins. The misfolding of proteins, making them dysfunctional and disease-causing, is likely associated with the failure of water molecules to congregate in clusters that properly interact with the protein. The development of remedies to assist with such diseases should therefore be focused on the restoration of water clustering at the protein interfaces. Water cluster “surface” Terahertz (THz) vibrational modes are especially important because they couple or “resonate” with THz-frequency “bending” vibrations of the amino-acid residues in proteins. [R]
Kinetic THz absorption (KITA) studies of protein folding recently revealed that the water network surrounding proteins is dynamically rearranged in milliseconds before the protein folds to its native state within the following seconds. Some 1000 water molecules are "brought into line" by one protein. What this means is that water actually controls how a protein decides to fold. Therefore, the use of Quantum Harmonic Terahertz Wave Resonance Technology dictates biological cell architectures. [R]
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The use of Quantum Harmonic Terahertz Wave Resonance Technology promotes cellular harmony. This is done via coupling of the THz electromagnetic field to the water clusters leading to “quantum coherence”. [R]
An expectation in the biological community is that life originated in water. Water provides the medium in which all biochemical reactions take place. The importance of water to living organisms is due to its peculiar features. The assembly of water molecules shows electromagnetic and electronic collective states that contain “quantum imprints or molds” for living cells which implies quantum coherency and quantum entanglement.
Water owes these unique properties to the polarity (i.e. dipole character) of its constituent molecules, which form bonds among each other as well as with other polar molecules. Biological systems exhibit macroscopic quantum properties and superconductive properties.
The implication goes also to the cosmic dimension, where the combination of interstellar (cosmic) dust and structured water provides a semi-conducting electromagnetic conduit. It could promote the quantum entanglement of microscopic (Planck level) and macroscopic (cosmic level) wave information as a connective principle in the fabric of reality! [R]
Water is key to the existence of life as we know it. Water is an information carrier. Water has the ability to store the information of molecules dissolved in it. Our bodies are made up of over 90% water. These body fluids literally resonate with different frequencies. Water molecules organize themselves in our bodies into honeycomb-like water structures. Structured water, also known as hexagonal water, is water where the molecules form a hexagonal cluster.
“To understand water is to understand the cosmos, the marvels of nature, and life itself.” - Masaru Emoto
"Water is the driving force of all nature.“ - Leonardo da Vinci
"A man of wisdom delights in water.“ - Confucius
Consequently, the potential of water to organize biological systems is also expected to play an active and essential role for any origin of life scenario. Quantum electrodynamics (QED) reveals that all molecules fluctuate in unison between two distinct configurations (the ground and the excited one) and in tune with the enveloping vacuum electromagnetic field.
Quantum Harmonic Terahertz Wave Resonance Technology gives rise to a unique field resulting in the collective dynamics of the water molecules; they start to behave as a single (quantum-like) object. Biological dynamics appears, therefore, as a close interplay between electromagnetism and chemistry, where fields are able to make the molecules interact through resonance, and molecules are able to regulate the field frequency through reaction energies.
It has been shown that electromagnetic fields affect both the degree of entanglement, and indicate that a coherent quantum entangled wave function exists. A striking finding tackled the observation that life systems, as studied in 550 biomedical articles and 80 reports about entanglement and superconductivity, showed distinct frequency patterns. This strongly suggests that coherence, entanglement and superconductivity may be prerequisites for life.
Researchers found that the beneficial biological effects related to the effects of in vitro or in vivo electromagnetic stimulation (defined as coherent) could be positioned on the range of the Pythagorean-scale producing “entangled quantum wave function”.
A healthy living system has a high level of coherency, while an unhealthy one shows a low level of coherency or even a high level of decoherence.
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In other words, this process helps harmonize your cells and exponentially increases absorption through enhanced endocytosis (taking in of matter).
We are, at our core, Hydro-Electric Beings consisting of roughly 90% water and massive amounts of ion channels that control our electrophysiology.
The Terahertz Frequency Wave primarily works with water channels (aquaporins) and hydrogen bonding for our benefit. In fact, the very structure of our DNA is held together through hydrogen bonding.
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Increased Bioavailability
In a process known as endocytosis (taking in of matter), applying the Terahertz Frequency Waves to the solution naturally increases the bioavailability of the ingredients by allowing more of the molecules to pass into the cell.​
The capacity of DNA, RNA, and proteins to catalyze energetic reactions and convey information depends on their vibrational states and phonon modes accessible using Terahertz Frequency Waves.
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STUDY
Terahertz waves facilitate the transmembrane transport of small molecules
Scientific Research
Formulated over many years of research to support all aspects of health and performance. Discover a new way to take your immune system to the next level! We are not just selling you a product here. Not only is Core Manna an amazing all-natural product, but it is also backed by the latest and most advanced research to help you live a healthier life, right now!
You can trace every known disease back to Glycoimmunology. Our Innate immune system controls the entire mainframe.
This is why Core Manna should be the foundation, or core, of anything else you do so that your body’s defenses are operating optimally allowing you to handle anything, anywhere, at any time.
Scientific Research
Glycoimmunology: ignore at your peril!
We are all glycoimmunologists. If you study a protein that is expressed on the surface of lymphocytes or dendritic cells or macrophages or any other mammalian cell, that protein is almost certainly glycosylated.
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https://onlinelibrary.wiley.com/doi/10.1111/j.1600-065X.2009.00800.x
The Role of the Mannose-Binding Lectin in Innate Immunity
The innate immune system, which includes mannose-binding lectin (MBL), recognizes a broad range of molecular patterns on a broad range of infectious agents and is able to distinguish them from self.
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https://academic.oup.com/cid/article/41/Supplement_7/S440/665932
Mannose-binding lectin and the balance between immune protection and complication
A pivotal link between the innate immune system and other functions is mannose-binding lectin (MBL), a pattern recognition molecule.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259613/
Glycosaminoglycans and infection
Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial pathogens, including viruses, bacteria, parasites, and fungi. Pathogens use GAGs at virtually every major portal of entry to promote their attachment and invasion of host cells, movement from one cell to another, and to protect themselves from immune attack. Pathogens co-opt fundamental activities of GAGs to accomplish these tasks.
Metabolic Glycoengineering: A Promising Strategy to Remodel Microenvironments for Regenerative Therapy
Metabolic glycoengineering (MGE) is an easy but powerful technology for remodeling the structure of glycan. MGE provides us an opportunity to reshape the microenvironment and evoke desired cellular responses.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940976/
Frequency Asked Questions
Question: Your label says "This product contains wheat, dairy, and soy. Ingredients may be produced in manufacturing facilities that produce other products which may contain soy, dairy, wheat, tree nuts, shellfish, fish, peanuts, and eggs, and may contain traces of all the above".
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Is it okay to take if I have a food allergy?
Answer: As always, you'll need to consult your healthcare provider. However, we believe we cracked the "Food Allergy Mystery". You can read about it here Food Allergies – The Battle Between Self vs. Nonself
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Question: Can I take Core Manna if I have a Dairy or Milk Allergy?
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Answer: We believe we may have solved the mystery of this type of allergic response. Learn more here "Milk and Dairy Allergies: Mechanisms of Core Manna Management"
Question: Does Wheat Germ Extract Contain Gluten?
Answer: No, wheat germ extract does not contain gluten. Wheat germ extract is made from the part of the wheat kernel that is removed when flour is made. This part of the wheat kernel is called the germ, which is high in health-promoting vitamins, minerals, protein, and essential fatty acids. Fermented Wheat Germ Extract contains a miracle molecule called Spermidine.
Since the germ is removed to make flour, it is gluten-free. Therefore, wheat germ extract is also gluten-free, making it safe for those with celiac disease and gluten intolerance.
Question: On the label it says that this product contains dairy. Can I take Core Manna if I have an allergy?
Answer: Legally, we must put that the product contains dairy even though MCT Coconut Oil is dairy free. MCT oil can be sourced from various ingredients including beef, pork, dairy, palm oil or coconut oil.
Question: I have an issue with soy products because I was told soy can mess with estrogen signaling. Should I consider taking Core Manna?
Answer: Yes! First, the soy found in Core Manna is an organically sourced NON GMO soy as opposed to GMO soy, which has been shown in research to have a negative impact on health.
Secondly, we’ve formulated Core Manna to have a synergistic impact on the phytoestrogens found in soy by adding compounds like Broccoli sprouts. Broccoli sprouts contain 30 to 100 times more sulforaphane than broccoli. It's a big deal because sulforaphane is a natural “estrogen blocker” – it parks itself in the estrogen receptors and stops the “bad” estrogens.
The general impression is one of certainty that soy isoflavones deliver many health benefits, including prevention of cardiovascular disease, cancer, and osteoporosis, as well as treatment of menopausal symptoms. Soy isoflavones also have tremendous benefits for cognitive function and the nervous system. The two major soy isoflavones are called genistein and daidzein. Soy is a unique food that is widely studied for its estrogenic and anti-estrogenic effects on the body. Studies may seem to present conflicting conclusions about soy, but this is largely due to the wide variation in how soy is studied. Results of recent population studies suggest that soy has either a beneficial or neutral effect on various health conditions. Soy is exalted as a health food by some, with claims of taming hot flashes, warding off osteoporosis, and protecting against hormonal cancers like breast and prostate. At the same time, soy is shunned by others for fear that it may cause breast cancer, thyroid problems, and dementia, though these claims have not been substantiated.
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